March 2014 Edition

IJASR Volume 2- Issue 1, March 2014 Edition 

All listed papers are published after full consent of respective author or co-author(s).
For any discussion on research subject or research matter, the reader should directly contact to undersigned authors.


Abdel-Haleem, A. A.

ABSTRACT: The present study includes ultrastructural aspects of molluscicidal effects of wild botanic aqueous extract, namely Za’ater plant (Origanum syriacum) on the gametogenesis of two terrestrial slugs, giant grey slug Limax maximus and tree slug L. marginatus. L. marginatus was more susceptible to this plant than L.maximus (LC90 are 445.1&460.2 for L.marginatus and L.maximus respectively). The present results revealed that Za’ater’s extract had adverse effects on gametogenesis of the treated slugs, including marked inhibition of the various stages of gametogenesis, besides intracellular accumulation of the toxic agents of Za’ater-plant. Therefore, the treatment of the tested slugs with LC90 of Za’ater extract can be recommended for controlling such slugs in the field, instead of using chemical pesticides that continuously pollute the environment.

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Histological and Scanning electron microscopic studies on the sensory organs of the terrestrial flatworm Bipalium kewense

Abdel-Haleem, A. A.1, Beltagi, S. M.2 and Ali, A, S.2

Abstract: The present work showed the fine structure and histology of the flatworm Bipalium kewense (Moseley, 1878) on the sensory organs (included sensory papillae, sensory pits and small eyes or eyespots). Both sensory papillae and sensory pits are situated at the peripheral edge of the shovel-head of the worm. On the other hand, numerous fine eyes (eyespots) are located within the margin of the dorsal headplate and along the body margin. Each eye is composed of pigment cells surrounding half moon-like lens and retinal cells. The present study suggested that the sensory papillae and sensory pits are chemoreceptors to test the food, humidity and salinity of the surrounding environment.

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ABSTRACT Mushrooms have long been attracting a great deal of interest in many areas of foods and biopharmaceuticals. They are well known for their nutritional and medicinal values. Mushrooms comprise a vast and yet largely untapped source of powerful new pharmaceutical products. In particular, and most importantly for modern medicine, they represent an unlimited source of polysaccharides with antitumor and immunostimulating properties. Recently, basidiomycete fungi have been used for the treatment of cancer. Many, if not all, Basidiomycetes mushrooms contain biologically active polysaccharides in fruit bodies, cultured mycelium, culture broth. Polysaccharides and polysaccharide-protein complexes from medicinal mushrooms may enhance innate immune responses, resulting in antitumor activities. In this review, in the search for the development of new anticancer drugs, the effects of polysaccharides isolated from medicinal mushrooms on tumor were studied.

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Microbiological, Biochemical and Functional Characterization of Helicobacter pylori infection.

M.Abdelrazik, and Khalil Alali

ABSTRACT  In 1979 Robin Warren, a pathologist in Perth, Western Australia, began to notice that curved bacteria were often present in gastric biopsy specimens submitted for histological examination.These organisms were not present within the gastric mucosa but were present in the mucus layer overlying the tissue [2]. Warren found that because they could never be isolated, they were ignored and ultimately forgotten by generations of physicians and scientists.  A young trainee in internal medicine, Barry Marshall, became interested in Warren’s observations, and together the two sought to isolate the organisms from biopsy specimens.Since the organisms had the appearance of curved, gram-negative rods, the investigators used methods for the isolation of Campylobacter species, including inoculating the biopsy specimens on to selective media and incubating the cultures under microaerobic conditions. Since most Campylobacters grow within 48 h under such conditions, plates without visible growth were discarded within 3 days. The initial cultures from approximately 30 patients were negative, but by chance one culture was incubated for 5 days over an Easter holiday and colonies were seen [60] subsequently, organisms were isolated from 11 patients. the organism was characterized and called Campylobacter pyloridis (now known as Helicobacter pylori). Following publication of this seminal report, investigators all over the world rapidly confirmed the presence of these organisms in the gastric mucus [62]. It had become clear that H. pylori infection was strongly associated with the presence of inflammation in the gastric mucosa (chronic superficial gastritis), and especially with polymorphonuclear cell infiltration (chronic active gastritis).

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